Several medications are used to treat, prevent, or lessen the frequency or severity of abnormal heart rhythms. This group of medications is called antiarrhythmics. 

Talking to your Doctor

By talking openly to your doctor, you will know what treatments are best for you. Your doctor can provide advice based upon your concerns, value and priorities; a process called shared decision-making. Even if you simply want to follow your doctor’s recommendations, it is important to have a conversation about what matters most to you.


These decrease the frequency or severity of abnormal heart rhythms, known as arrhythmias. These medications include:

  • Beta blockers- such as metoprolol, carvedilol, nadolol, and atenolol
  • Calcium channel blockers- such as verapamil and diltiazem
  • Potassium channel blockers- such as amiodarone, sotalol, and dofetilide
  • Sodium channel blockers such as flecainide and propafenone

Help to prevent blood clots that can cause stroke. Newer anticoagulants include apixaban (Eliquis), dabigatran (Pradaxa), and rivaroxaban (Xarelto).

Frequent blood tests are not required with these medications.  Warfarin (Coumadin) is commonly used in patients with atrial fibrillation and mechanical heart valves. Patients taking warfarin require periodic blood tests (INR) to ensure that the blood is appropriately thinned.

Lower elevated blood pressure (hypertension) and prevent complications from high blood pressure such as heart attack and stroke.

Decrease cholesterol levels in the blood. Lower cholesterol helps to prevent coronary artery disease and heart attacks.

Help to decrease fluid and salt in the body. Sometimes called water pills, these are used to reduce the buildup of fluid which occurs in heart failure. People taking diuretics may need to take extra potassium to maintain safe levels in the blood.